A study published in the Journal of Alzheimer’s Disease shows that nutritional supplementation with magnesium threonate (Magtein) may be effective at reversing cognitive impairment and returning cognitive function almost back to normal ability relative to age. Magnesium threonate is a compound designed to help magnesium to cross the blood brain barrier so that it can increase brain synapse density on restoration of certain cognitive abilities.
In this randomized, controlled, double-blind study, the researchers evaluated the effect of magnesium threonate on cognitive ability in four cognitive domains: executive function, working memory, attention, and episodic memory at baseline, week six, and week 12. The subject population included 44 men and women, aged 50–70, with self-reported memory loss and sleep disorder. The mean subject age was 57.3±5.2 years, with 71% being female.
Following 12 weeks of magnesium threonate use, there was an average increase of 10.3±3.8% in executive function as measured by the Trail Making Test, such that their speed was close to that of their age-matched controls. The researchers concluded that magnesium threonate is effective in improving cognitive ability almost back to normal levels relative to age.
