The transaction will result in Palm Belgian Craft Brewers becoming part of Bavaria.
Bavaria plans to fully own Palm by 2021.
The two family-owned breweries will have a combined production capacity of 6.5 million hectoliters in 2016.
The stake acquisition is in line with Bavaria's strategy to strengthen its craft beer portfolio. The deal will enable Palm to strengthen and accelerate its growth plans.
The acquisition will allow Palm to gain access to Bavaria's international network, while Bavaria will accelerate its access to Belgian retail channels and hospitality sector.
Both companies plan to work on the merger of the two family-owned businesses in the coming months.
Palm and De Hoorn breweries in Steenhuffel and Rodenbach brewery in Roeselare are part of the majority stake acquisition.
Bavaria has presence across 120 countries in the world offering brands such as Bavaria Premium, Swinckels', and 8.6.
Palm owns five breweries in Belgium with an annual capacity of around one million hectoliters and is also known to produce specialty beers such as Rodenbach, Brugge, Steenbrugge, Cornet, Arthur's Legacy and Estaminet.
Bavaria board head Jan-Renier Swinkels said: "Palm has an important position in the Dutch market and we see opportunities for international growth."
