Although one of the artificial ingredients had already been removed from the FDA’s approved list, six of the ingredients — benzophenone, ethyl acrylate, eugenyl methyl ether, myrcene, pulegone, and pyridine — are currently commonly used as imitations of natural mint, citrus, and cinnamon flavors. Benzophenone for instance, has been found in breakfast cereals, baked goods, and frozen dairy products, while pulegone is used as a peppermint or spearmint flavoring in mints and chewing gum.
On October 5, the FDA announced that it will be removing these additives from its approved list, despite the fact that the ingredients are only “used in very small amounts,” based on the data findings in petitions signed by activist groups, including the Center for Environmental Health, Center for Food Safety, and Center for Science in the Public Interest.
“While the FDA’s recent exposure assessment of these substances does not indicate that they pose a risk to public health under the conditions of their intended use, the petitioners provided evidence that these substances caused cancer in animals who were exposed to much higher doses,” the FDA concluded in a press statement.
The data presented by the advocacy organizations in the original 2015 petition was based on studies like the toxicology report published in the National Toxicology Program’s Technical Report Series in 2006. The study linked benzophenone consumption in rats to increased incidence of leukemia, histiocytic sarcoma, as well as kidney and liver problems.